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The present feature article highlights our recent efforts to develop modular synthetic platforms in macromolecular synthesis.
Microorganisms are used as synthetic platforms of systems biology where biochemical pathways are engineered into the host metabolic network.
In this context, 1,3-dicarbonyl compounds are exceptional synthetic platforms due to the presence of four contiguous reaction sites.
Thus, feeder-free, chemically defined synthetic platforms have been developed, but are mostly confined to typical polystyrene culture plates.
The best candidate pathways are then engineered within a metabolic network of microorganisms that serve as synthetic platforms for synthetic biology.
These pathogen-like particles, or PLPs, can come from a variety of sources, ranging from fully synthetic platforms to biologically derived, self-assembling systems.
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With the tunable oxidation states of conducting polymers, we expect this synthetic platform can synthesize a wide range of nanostructured metals with specific size, shape and properties.
The ability to define a versatile synthetic platform will enable many chemistries and architectures to be studied.
In the contribution, we explore an efficient synthetic platform to purposefully fabricate hollow mesoporous NiCo2S4 (HM-NCS) ellipsoids for advanced electrochemical supercapcitors (ECSs).
The successful generation of these macrocycles demonstrates the feasibility of the new DOS strategy as a synthetic platform for library generation.
We are on the verge of producing "synthetic cells," or protocells, in which some, many or all of the tasks of a real biological cell are harnessed into a synthetic platform.
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