Exact(7)
Garner, A.R. et al. Generation of a synthetic memory trace.
Garner, A. R. et al. Generation of a synthetic memory trace.
In this study, the authors created a synthetic memory trace derived from the conjunction of a context and an artificially activated ensemble of neurons.
Synthetic memory circuits have been designed and built in vitro and in vivo based on diverse mechanisms, such as oligonucleotide hybridization, recombination, transcription, phosphorylation, and RNA editing.
Here we discuss strategies for building synthetic memory circuits, their use as research tools, and future applications of these devices in medicine and industry.
Here we describe the role of transcriptional regulation in both natural and synthetic memory networks and discuss the potential applications of engineered memory networks in medicine and industrial biotechnology.
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We apply the technology to yeast prions, developing sensors to track their aggregation states and employing prion fusions to encode synthetic memories in yeast cells.
"Synthetic Biological Memory and Counter Circuits," Kavli Frontiers of Science, Irvine, CA, November 13, 2009.
As a practical device, the toggle switch forms a synthetic, addressable cellular memory unit and has implications for biotechnology, biocomputing and gene therapy.
At various times, governments have been convinced that steel, nuclear power, synthetic fuels, semiconductor memories, and fifth-generation computers were the wave of the future.
Memory of past environments can also confer a fitness advantage in some situations[2], and synthetic biological two-state memory switches have been built in both prokaryotes[3]and eukaryotes [4].
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