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The chapter concludes by considering future synthetic challenges in this area.
To this end, obvious synthetic challenges have been identified and solutions have been proposed that offered high probabilities for success.
This Letter describes the synthetic challenges in synthesising key 1,4-cis-substituted cyclohexylamide intermediate 1 for our research programme.
Finally, we discuss the synthetic challenges, drug delivery outlooks, and perspectives of PHB-based drug delivery systems.
Related opportunities at the interface of synthesis, biology and medicine include studies on daphnanes, gnidimacrin and apoptolidin, formidable synthetic challenges with unique clinical promise.
We also consider their potential application to current synthetic challenges, including the development of catalytic amide formation, the synthesis of therapeutic peptides and the preparation of modified peptides and proteins.
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Due to its peritectic formation feature, there is a synthetic challenge to produce single Co5Pr-D2d phase.
Glycosylating complex molecules remains a major synthetic challenge, making it hard to explore carbohydrate diversity in biologically active glycosylated natural products and their derivatives.
The grafting of Cr III) coordination complexes as capping units onto polyoxometalates (POMs), still remains a considerable synthetic challenge due to the difficulty in replacement of aqua-ligands in [Cr(H2O 6]3+ complexes.
This particular architecture which appears simple comprises a significant and attractive synthetic challenge indeed.
Conventional organic dyes readily photobleach upon prolonged irradiation, and tuning their optical properties is a general synthetic challenge [72].
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