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A series of retinoids designed to interfere with the repositioning of H12 have been synthesized to identify novel RARγ antagonists based on the structure of known RARγ agonists.
Review/Analysis Methods: Following a systematic screening process, the included articles were analyzed and synthesized to identify patterns, variations, and relationships.
METHODS: To this end, analogues of 4-HC were synthesized to identify the contributions of individual cyclophosphamide metabolites to cytotoxicity.
These themes were further synthesized to identify whether they could emerge as important domains of ophthalmic quality of life.
Pyrazolone based affinity probes were synthesized to identify high affinity binding partners and ascertain a potential biological mode of action.
RNA was extracted from normal and proband's cultured skin fibroblasts and cDNA was synthesized to identify EYA1 aberrant transcripts.
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Libraries of mifepristone analogs, MP-Acids, were designed and synthesized to increase the chances of identifying GR antagonists that possess liver-selective pharmacological profiles.
The catalyst was synthesized and characterized to identify the active vanadyl pyrophosphate phase.
Twenty-six NPG analogs and related structures were synthesized and tested to identify more active inhibitors.
The study on chemical and phase composition, thermal stability, texture and reducibility of the synthesized samples allowed to identify their active phases in toluene combustion.
We synthesized the literature to identify four critical success factors (CSFs) known to be effective in the successful management of the FEI process.
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