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Potent and selective cathepsin B inhibitors have previously been synthesized based upon the natural product cysteine protease inhibitor E-64.
A series of phosphotyrosine containing cyclic peptides was designed and synthesized based upon the phage library derived cyclopeptide, G1TE.
Novel carborane-containing estrogen receptor (ER) modulators, carbamate and thiocarbamate derivatives 5 and 6, were designed and synthesized based upon the m-carborane bisphenol skeleton.
In this study, a series of phosphotyrosine containing cyclic pentapeptides were designed and synthesized based upon the phage library derived cyclopeptide, G1TE.
These inhibitors were designed and synthesized based upon our X-ray crystal structure of inhibitor 1 bound to SARS-CoV 3CLpro.
Using this route, a series of cyclic peptides that do not rely on phosphotyrosine or its mimics were designed and synthesized based upon the phage library-derived cyclopeptide, G1TE.
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Two highly selective red-emitting fluorescent "OFF-ON" probes (3a and 3b) with a BODIPY core were designed and synthesized, based on the recovery of fluorescence upon the cleavage of the fluorescence quenching unit of 2, 4-dinitrobenzenesulfonyl (DNBS) by biothiols.
The second-strand cDNA was synthesized based on the P2 sequence.
PAMNPs were synthesized based on the poly acylic acid) (PAA -coated magnetite nanoPAA -coatedwhich was synthesized by the magnetite polyol method.
Amplimers were synthesized based on cDNA sequences from GenBank (2004).
Terpenoids are synthesized based on isoprene (C5) units.
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