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Kosuri, S. & Church, G. M. Large-scale de novo DNA synthesis: technologies and applications.
Recent advancements in DNA synthesis technologies will facilitate large-scale recoding of support genes to protect from MazF activity.
Throughout the 1980s and '90s and in the early 2000s, DNA synthesis technologies became increasingly time- and cost-efficient, thereby enabling steady advance and more ambitious experimentation.
The project aimed to develop formal models for such heterogeneous systems, a software environment for the design of such systems, and synthesis technologies for implementation of such systems.
Oligonucleotides, usually 25-mers, are directly synthesized onto a glass wafer by a combination of semiconductor-based photolithography and solid phase chemical synthesis technologies.
The continuously dynamic-controlled combustion synthesis (CDCCS) was developed based on the continuous fluidization and combustion synthesis technologies.
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Still, DNA synthesis technology is improving.
Hydrothermal synthesis is a material synthesis technology.
But the smallpox virus has a genome almost 200,000 bases long, putting it out of reach of current synthesis technology.
The synthesis technology is operated at near-critical conditions.
A surface modifying and ultrasonic synthesis technology is also demonstrated.
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