The synthesis score appeared to be a reasonably strong instrument, although the scores explained less than 1%% of the trait variance for circulating 25(OH D and 1,25(OH)2D.
Two scores were calculated by summing up all appropriate SNPs in each individual: (1) Synthesis score: genes encoding proteins involved in 25(OH D synthesis (CYP2R1 rs10741657, DHCR7 rs12785878) [ 29]; and (2) Metabolism score: genes encoding proteins involved in 25(OH D metabolism (CYP24A1 rs6013897, CYP27B1 rs10877012) [ 29].
According to the Hotelling-T test, the left-behind children scored significantly lower on the HRQoL synthesis scores than the non-left-behind children (F = 6.14,P < 0.05).
Children aged between 2 to 4 were at remarkably higher risk of lower HRQoL synthesis scores, while children aged 8 to 12 showed a better HRQoL scores in school performance subscale.
There was a total of 608 (44.61%) left-behind children or adolescents, and they scored significantly lower in terms of the HRQoL synthesis scores (F = 6.14, P < 0.05), Physical Functioning (H = 33.18, P < 0.05), Emotional Functioning (H = 24.99, P < 0.05) and Social Functioning (H = 12.24, P < 0.05), compared with the non-left-behind.
According to the Hotelling T test for the left-behind children/adolescents, their HRQoL synthesis scores were found to be significantly associated with gender, age, father's education level, duration of parents' absence and the intervals of mother coming back home to visit the children/adolescents (Tables 4 and 5).
The biggest cluster of PrDs (502 proteins) contained the proteins involved in viral transcription, translation, and protein synthesis (LLR score, 6.69), with multiple molecular functions and belonging to different GO terms.
Best evidence synthesis was scored according to Cochrane criteria.
To exclude that differences in the experimental parameters employed for the proliferation assays versus RT-PCR analysis could account for the lack of EP3 detection, we investigated the effect of serum withdrawal, since PGE2-dependent DNA synthesis was scored in cells deprived of serum, while RT-PCR analysis was performed on samples from serum-fed cultures.
The theory of algorithmic composition usually distinguishes between score synthesis (the computer-aided working out of a composition, usually for traditional acoustic instruments) and sound synthesis (the computer-aided working out of a synthetic sound that can only be heard through loudspeakers).
Other important representatives of early score synthesis are Gottfried Michael Koenig and Iannis Xenakis.
