The compounds provide a starting point for the synthesis of novel tools to decipher Hsp70 biology.
To better understand the molecular basis for these dissimilarities, we report here the synthesis of chemical tools for three Hsp90 inhibitor classes.
The combination of a multiproxy dataset evidenced by the detailed synthesis of lithic tools and pottery, faunal remains, pollen and charcoal assemblages has been integrated with a GIS approach and a regional cultural and palaeoenvironmental contextualization.
Overall, these findings may facilitate the design and synthesis of novel therapeutic tools for the treatment of MI.
This study provides new insights for the development of anti-thyroid drugs, as well as for the synthesis of novel pharmacological tools designed to investigate iodide transport mechanisms at cellular and molecular levels.
The key learning from this chapter include the synthesis design process, use of tools, synthesized output files and a tutorial which describes on how to perform a synthesis.
In recent years, the capability of synthetic biology to design large genetic circuits has dramatically increased due to rapid advances in DNA synthesis technology and development of tools for large-scale assembly of DNA fragments.
This paper systematically investigates issues relevant to the kinematic synthesis of hexapod-based machine tools.
Here we present a synthesis of how these genetic tools have been, and could be, used to answer questions directly relevant to aspen ecology and management.
In this review, we summarize the results obtained so far concerning the fluorescent labeling of plant hormones, highlighting the basic steps leading to the design and synthesis of these compelling molecular tools and their applications.
