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This measure is denoted by synergy strength.
However, no other significant correlation between synergy strength and genotype could be observed (Fig. 3A).
This model laid the basis for detection of synergy strength of compound combinations.
We next computed this synergy score and applied hierarchical clustering to the data matrix of the synergy strength (Fig. 3A).
The curve, which separates synergistic from antagonistic combinations, is computed from the previously determined fits, which serves as basis for the synergy strength.
In summary, we provide a tool for the measurement of synergy strength for combination perturbation experiments that might help define pathway topologies and direct clinical trials.
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We also evaluated the underlying synergy strengths produced by agent pairs from the perspective of GO functions.
Biological materials with hierarchically laminated structures usually exhibit a good synergy between strength and fracture toughness.
The experimental results show that the ultrafine-grained Ni/coarse-grained Cu laminated composites with a thickness ratio of 20 1 have a good synergy of strength and ductility.
Music executives prefer to talk of synergy, rationalisation and strength through partnership.
The hierarchical structures in biological materials have shown a good synergy of high strength and good fracture toughness (damage tolerance).
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