Sentence examples for synergy response from inspiring English sources

To determine if altering Mcl-1 or Bcl-2 levels could affect the Hipp+Dxr synergy response, we generated Eμ -Myc lymphomas overexpressing these anti-apoptotic proteins.

The AsPC-1 cell line was chosen for these studies since it had (i) the highest uptake and accumulation of [H]troxacitabine among the four cell lines, and (ii) a good synergy response.

Although these results do not rule out a contribution from tumor cell extrinsic responses to the Hipp+Dxr-response in vivo, they do indicate that components of the intrinsic cell death pathway are major modifiers of the Hipp+Dxr synergy response in vivo and do so at least in part by affecting cell sensitivity to Hipp and Dxr.

It has been proposed that p110β could provide a mechanism for signaling downstream of GPCRs in non-hemopoietic cells where the Gβγ-responsive isotype p110γ is not expressed (Guillermet-Guibert et al., 2008) and that synergy of response by combined GPCR and RTK activation might be the biological role of the p110β isotype (Kurosu and Katada, 2001; Kulkarni et al., 2011).

In this way, the controller can account for the therapeutic regime-dependent influence of medications and inter-medication synergy on clinical responses, while making use of dose-response measurements for online adaptation of dose-response models.

Basically, it could not validate synergy because the response to one odor depends on the others, particularly because the animal could move freely from one odor to another within a very short period.

Moreover, the effectiveness of the adjuvant combinations should be based on a synergy between immune response enhancers and delivery systems.

We observed synergies in the response of regulating hydrological ES to LULCC but at the same time also trade-offs with provision of food and fodder.

The absorbed O2 reacts with Li+ which reaches the catalyst at the channel created through the interaction with rGO nanosheets to form LiO2. The formation of LiO2 would increase the response and synergy with the oxygen-containing species, which were absorbed using CCO nanoparticles in order to produce the Li2O2 films.

The Regional Directors Group was created in 2003 to enhance the synergy of the United Nations response to HIV in Latin America and the Caribbean.

However, it has been previously shown in mice that engagement of the adaptor protein CARD9 is crucial in facilitating NOD2-initiated p38 and JNK signalling, with the two proteins working in synergy to mediate this response [17].