Jack is part corporate jackass (he tells Liz that Jack Welch is "the greatest leader since the Pharaohs," and says things like "We're effectively synergizing backward overflow"), part self-infatuated charmer, and part oblivious big baby, yet the friction between him and Liz develops into friendship.
We further show that superactivation of the prosurvival PI3K-AKT signaling pathway limits the efficacy of a PARP single-agent treatment, and that PARP and PI3K inhibitors effectively synergize to suppress tumorigenesis in human prostate cancer cell lines and in a Pten/Trp53-deficient mouse model of advanced prostate cancer.
In this study, we found that the otherwise most potent inflammatory cytokine, IL-17, could in fact effectively synergize with IFN γ and TNF α in inducing immunosuppression by promoting inducible nitric oxide synthase (iNOS) expression in MSCs.
Wang Q, Li SH, Wang H, Xiao Y, Sahin O, Brady SW, et al. Concomitant targeting of tumor cells and induction of T-cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer.
Wang, Q. et al. Concomitant targeting of tumor cells and induction of T-cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer.
Bringing chemistry and biology much closer and blurring the boundaries between disciplines is creating new opportunities to probe and understand biology; both disciplines play key roles and need to join forces and work together effectively to synergize their impact.
We're talking about synergizing.
This is one bit of New York synergy that won't stop synergizing.
Synergizing earned, owned, and paid channels is relatively easy.
We also proposed synergizing these technologies into newer hybrid technologies.
Both effects would synergize in reducing levels of functional mitochondria.
