Combination of U0126 and Akti IV showed significantly enhanced or synergized effects on NIS protein expression (Figure 6B, upper panel).
Mammalian cells harboring replicating L. pneumophila exhibits a strong resistance to exogenous cell death stimuli [30], [31], probably by synergized effects resulted from NF-κB activation and the activities of some effectors such as SdhA and SidF, which have been shown to contribute to such resistance by different mechanisms [32], [33].
A solid amine fiber VF AM TETA was designed with viscose (VF) substrate for efficient CO2 capture, where its hydroxyl groups could serve synergizing effect in CO2-amine reaction.
Although the previous report did not demonstrate the synergizing effect of hIL-32 with Toll-like receptor signaling in vitro [ 42], our results suggest that continuous exposure to hIL-32 in relatively low concentrations would have an influence on Toll-like receptor signaling of splenocytes in vivo.
This study shows that Mir1-CP is effective against Lepidopteran pests and may be one of the most toxic endogenous plant defense proteins known and that only 60 ppb of Mir1-CP are required to synergize the effects of Bt-CryIIA concentrations ranging from 0.40 to 1.0 ppm.
For example, venoms can synergize the effects of PDVs [ 18, 19] and can interfere with host's humoral [ 20- 22] and cellular immune components [ 23- 26].
Non-DL-PCBs can both antagonize and/or synergize the effects of DL-compounds, it depends on the response, the dose, and the concentrations [ 48, 59].
A growing number of early clinical trials are exploring attempting to synergize the effects of HDAC inhibitors and NFKB interfering proteasome inhibitors to treat solid tumors, with variable reported success [ 29, 30].
However, overexpression of both proteins clearly increased/potentiated the TGFβ effect, suggesting that these two proteins synergize their effect downstream of TGFβ.
However, that was more effective when given in combination with convention therapies to synergize the effect of such combination therapy [ 310– 310].
