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A great astronomer (who sadly died young), Beatrice Tinsley, is known as one of the greatest creative theoreticians in astronomy and was renowned for her breadth and ability to synergize a great deal of information and see many linkages.
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The BCL-XL-selective inhibitor A-1155463 showed no single agent activity and did not synergize with A-1210477 in BCL2 High NHL cells in vitro, further emphasizing the importance of BCL-2 inhibition in the BCL2 High subtype.
Herein, we have developed an efficient strategy to steer the migration of plasmonic hot electrons through a well-designed hybrid structure that synergizes a "surface heterojunction" with a Schottky junction.
Eisenberg and co-workers have now synergized a number of developments from their lab and others to perform the highest resolution structure-based drug design study to date for inhibitors of amyloid toxicity.
It is likely that the addition of an anti-estrogenic compound would not synergize with a histone deactetylase inhibitor in an already estrogen-free environment.
It has also been demonstrated that a Dact1 paralog can synergize with a co-expressed Dvl protein to activate the Wnt/β-catenin pathway under some conditions.
Users can query the database to easily obtain standardized information about the molecular determinants of sensitivity or resistance of melanoma to a given treatment, the compounds that can synergize with a given treatment, as well as the molecular determinants of toxicity of a given treatment.
Our results shed light on a more direct and upstream cause of the knockout phenotype that may synergize with a decline in antioxidant defenses.
Yet those perfect summer days when sun, temperature and gentle breeze synergize into a full-body caress make up for the torturous times.
Today's studies come on the heels of a year of damning evidence for these pesticides: three separate studies in the last year confirmed that low-level exposures to neonicotinoids synergize with a common pathogen to dramatically increase bees' susceptibility to infection and the likelihood of death.
Interestingly, while both signaling cascades counteract each other on the CRH proximal promoter, they synergize on a synthetic promoter containing 'positive' response elements.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com