The outcome measures are overall survival, palliation of symptoms, performance status, analgesic usage, toxicity, quality of life, tumor response, and recurrence/progression-free survival.
Clinical follow-up with documentation of symptoms, performance status, physical examination, and laboratory tests were done monthly.
The general approach to managing malignant effusions is determined by symptoms, performance status of the patient, expected survival and response of the known primary tumor to systemic treatment.
Baseline measurements included documentation of all symptoms, performance status, physical examination, laboratory tests (including blood counts, kidney function, and liver enzymes), and a diagnostic CT-scan.
Clinical factors that may correlate with survival include those related to patient age, presenting symptoms, duration of symptoms, performance status, tumour volume, extent of resection, and timing and dose of radiotherapy (Berger et al, 1994; Lote et al, 1997).
Patients records were reviewed to obtain baseline characteristic at the time of diagnosis (clinical stage, presence of B symptoms, performance status, bone marrow involvement, involvement of extranodal sites, mediastinal lymph node involvement, LDH, IPI score, PIT score).
We found that these women have a very small likelihood of experiencing symptoms of recent onset and high frequency, which led us to safely remove these women from symptom performance calculations.
Secondary endpoints include patient-perceived patient-physician communication symptom burden over time, and oncologists' symptom management performance (predefined thresholds of symptoms compared to oncologists' pharmacological, diagnostic or counselling actions [structured chart review]).
Patients with advanced-stage cancer commonly have multiple symptoms, poor performance status, and limited life expectancies.
Treatment choice is largely based on the number of BM, the presence of BM-related symptoms, and performance status.
This paper examines how two proposed cognitive vulnerabilities of social anxiety, the fear of negative evaluation, and looming cognitive style may combine with socially demanding situations in predicting social anxiety symptoms and performance deficits.
