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Table 2 shows the risks of RA in patients with symptomatic OA or OA-related surgery.
For the complete sample, 29% had radiographic OA, 17% had bilateral radiographic OA, 16% had symptomatic OA, and only 6.5% had bilateral symptomatic OA.
Not all histopathologic features associated with OA were associated with symptomatic OA.
5 The incidence of symptomatic OA is elevated in middle-aged individuals and the development of OA also requires a long time.
Radiographic OA, defined by the presence of osteophytes is much prevalent than symptomatic OA.
Biomarkers that identify individuals likely to develop OA, especially symptomatic OA, can help target preventative and therapeutic strategies.
This study compared the efficacy of the COX-2 specific inhibitor valdecoxib with naproxen and placebo, in treating symptomatic OA of the hip.
Parallel definitions apply to symptomatic OA.
It was also not possible to standardize symptomatic OA since all studies defined symptomatic OA differently.
A parallel representation applies to symptomatic OA and bilateral symptomatic OA.
Hence, the current findings relate to obesity and symptomatic OA.
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