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Optimization of symptomatic medications; 5.
Consistently strong evidence was found for the positive effect of prophylactic and symptomatic medications.
Limited evidence exists that symptomatic medications, such as Almotriptan [26] and Rizatriptan [31], improve patient vitality.
Of the 51 CM subjects, 48 were overusing symptomatic medications and they also fulfilled criteria for medication overuse headache (MOH).
During the entire treatment period, they were allowed symptomatic medications such as paracetamol, but triptans and opioids were disallowed.
The intake of symptomatic medications was reduced of about 12%, but the difference was not statistically significant.
The evidence of prophylactic and symptomatic medications effect toward the improvement of vitality and fatigue reduction is limited.
Unfortunately, patients with <50 % decrease in headache frequency (all belonging to NR-group) continued to overuse symptomatic medications.
Chronic headache can predispose to medication-overuse headache (MOH) with over utilizing different symptomatic medications [10, 11].
CCH sufferers often overuse symptomatic medications to treat CH attacks and may develop medication overuse headache (MOH) in addition.
In 34 of these patients (85%) overuse of symptomatic medications was observed at the onset of treatment.
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