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"What do you make of it?" "Symptomatic and significant," says he, "but not important".
85 Sadly, RHD diagnosis in Africa is usually established at an advanced stage of the disease, when severe valve lesions become symptomatic, and significant intervention is indicated.
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The T1 values were longest in patients with severe symptomatic AS, and significant difference in T1 values were found between the groups with severe asymptomatic and symptomatic AS.
Patients had either Binet Stage C and/or symptomatic disease and significant coexisting conditions as reflected by a CIRS score higher than 6, or a creatinine clearance of 30 69 mL/min.
266 Biochemical response has been demonstrated in 40 60% of patients, while symptomatic improvement and significant tumour shrinkage have been reported in 40 70% and a median of 10 15% of patients, respectively.
It is interesting to note that in the drug-induction study of Kaufmann et al, patients randomized to droxidopa had the greatest symptomatic, and statistical significant improvement in the dizziness/lightheadedness score, which did not reach significance in our study.
The efficiency of CF correction can be clinically manifested as the change in sweat chloride levels (<40 mM/L in normal individuals vs >60 mM/L in symptomatic CF patients) and significant improvement in the lung function (as measured by FEV1) of CF patients.
It is highly symptomatic and associated with significant impairment.
Nevertheless, no matter which technique of LCSD was used, perioperative complications were minor and significant symptomatic relief for the affected patients after LCSD has uniformly been observed.
In conclusion, CE is effective for stroke prevention when there is significant symptomatic and asymptomatic carotid stenosis, as low mortality and morbidity may be achieved in an experienced center.
Duration of antibiotic treatment in this indication is usually short-term: in a placebo-controlled clinical trial a significant symptomatic and bacteriological short-term benefit was observed in the therapy of uUTI with three-day treatment with nitrofurantoin, compared to placebo.
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