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Grey and white matter images were modelled separately in terms of group (control, presymptomatic, symptomatic), age, gender and total intracranial volume (all mean centred).
Following ethical approval, data were collected retrospectively for each presentation of breast cancer: method of presentation/diagnosis (MRI, mammography, symptomatic), age at diagnosis, cancer type, grade, size, presence of DCIS, lymphovascular invasion (LVI), nodal status and tumour subtype.
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To evaluate the performance characteristics of B-scan ultrasonography (US) as a diagnostic test for the detection of retinal tears in acute symptomatic age-related posterior vitreous detachment (PVD).
At symptomatic ages, we find reduced morphological complexity in the neuromuscular junction.
In contrast to previous reports, we find no evidence of either motor or sensory neuron loss at symptomatic ages.
We find no evidence of motor or sensory neuron loss in the Cra1/+ mice at symptomatic ages.
We find no loss of either motor or sensory neurons at symptomatic ages; instead, our analysis identifies decreased complexity of neuromuscular junction synapses, with associated muscle fiber abnormalities.
In conclusion, DTI with fibre tractography allows for in vivo 3D visualisation of part of the pelvic floor support, with reliable visualisation of the anal sphincter complex, perineal body, puboperineal muscle and the internal obturator muscle in women with pelvic organ prolapse (POP) as well as in symptomatic age-matched controls and asymptomatic nulliparous women.
They fed well initially but became symptomatic aged between 1 and 2 days with generalized tonic-clonic seizures.
Eligible patients will be symptomatic, aged 18 to 60 years and have clinical and radiolographic evidence of FAI.
We studied differences in the lipidomes of wild-type (WT) and SOD1(G86R) mice at pre-symptomatic and symptomatic ages (Supplementary Material, Fig. S1).
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