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To investigate which cognitive and affective features contribute most to responder/non-responder group separation during a switching trial with atypical antipsychotic.
The measures were selected because they required planning (Digit-Span Backward), inhibition (Stroop), and task switching (Trial B), all of which were crucial for PM tasks.
Verbal interference control was measured through the inhibition trial, and interference set shifting through the inhibition switching trial, of the Color-Word Interference Test (D-KEFS) 71, with additional information about the number of inhibition and inhibition-switching errors.
However, an open-label switching trial in patients who required alternative IOP-lowering therapy because of tolerability issues demonstrated a significant reduction in IOP after 3 months when patients were switched from latanoprost 0.005% to TRAV (n = 476) [ 25].
Examples of each experimental manipulation and the task switching trial temporal structure are depicted in Fig. 2. In a within-subject design, performance on the Stroop test and the task switching paradigm was investigated.
It therefore includes the largest switching trial (the International Exemestane Study), which shows a significant overall survival benefit.
Similar(54)
Trials are grouped into initial treatment trials, sequencing or switching trials, and extended treatment trials.
All four of the OS-positive AI trials have been switching trials.
Patients in substitution trials were randomised shortly after diagnosis, whereas those in switching trials were randomised at the switch point.
To find the potential priming or facilitating effect that might hide behind the executive function, we observed the brain activations in con_CON < all switching trials and incon_INCON < all switching trials, separately.
Thus, the switching trials should engage higher brain activities than repeating trials because they engaged more endeavors in the switching process.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com