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To help understand the determinants of TCR specificity, we studied a parental and engineered receptor whose peptide specificity had been switched via molecular evolution.
The NAD 3020 has four inputs that can be switched via the front panel – Aux, Tuner, Phono, Tape.
During the evolution of the apicomplexan LDH, however, specificity switched via an insertion that shifted the position and identity of this 'specificity residue' to Trp107f.
Another switchable adhesive system, based on a change in contact area and crack-trapping, was presented by Nadermann et al. 8 A metastable film-terminated architecture is switched via air pressure between a collapsed and uncollapsed state; the two states lead to different adhesive properties.
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Our investigations indicate that fringing electric fields lead to switching via intermediate 90° domains even in the absence of substrate or clamping effects for films of sufficient thicknesses, and via 180° rotations at smaller thicknesses.
Tong et al. [22] applied exponential synchronization for stochastic neural networks with multi-delayed and Markovian switching via adaptive feedback control, Yan and Yu [23], Lio and Yu [18] studied exponential synchronization for some well-known classical dynamical systems.
And I wouldn't be surprised if the Nexus 7 line picks up even more momentum now that Google has updated its base specs, and will soon add more software features, like user account switching, via Android 4.2.
HLTF facilitates template switching via its double-stranded DNA translocase activity (Blastyak et al. 2010).
DCs are thought to activate B cells and trigger their class switching via the production of various cytokines.
However, the IS insertions could hypothetically alter capsular gene expression, or promote capsule switching via rearrangement or horizontal transfer.
Accordingly, BAFF expression by synovial fibroblasts in response to TLR signaling has been shown to promote Ig class switching via AID induction [ 19, 20].
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