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3. Tacrolimus could be switched safely to sirolimus.
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The system should be capable of switching safely and predictably between a stiff spring and high damping mode (for handling) as well as a soft spring and low damping mode (for ride comfort).
Cancer patients receiving stable doses of TTS FE or TTS BU can be safely switched to the alternative transdermal opioid.
The PIVOT trial examined whether patients with suppressed viral load on combination antiretroviral therapy could be safely switched long-term to ritonavir-boosted protease inhibitor (PI) monotherapy.
Patients with severe infusion reaction or anaphylaxis to cetuximab can be safely switched to pannitumumab.
In addition, patients initiated on tamoxifen may be safely switched to letrozole, if indicated (e.g., for SAEs).
An early trial in open-heart surgery patients [ 4] documented that patients on other forms of CPAP ventilation may be safely switched to APRV.
National guidelines indicate that patients can be safely switched to oral therapy on the same day they meet criteria for clinical stability.
According to the above, patients can be safely switched from oral alendronate to zoledronic acid 5 mg infusion with maintenance of therapeutic effect for at least 12 months.
These 11 patients have now received ~3 years of treatment with agalsidase-α, and the results suggest that patients with Fabry disease receiving agalsidase-β can be safely switched to agalsidase-α with no loss of efficacy.
Similarly, in psoriasis, individuals can be safely switched without a washout period from the TNF agent etanercept to ustekinumab, a monoclonal antibody that targets IL-12 and IL-23 (Griffiths et al., 2010).
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CEO of Professional Science Editing for Scientists @ prosciediting.com