The fluorescence "switch ON" state of a MB can increase up to 200-fold when hybridized with the target nucleic acid [2].
The transition between a MB fluorescence "switch OFF" and "switch ON" state enables the differentiation between unbound and bound probes with background signal-to-noise ratio that could exceed 200, hence making it an ultrasensitive probe for nucleic acid detection [9 15].
Due to their high stiffness, CNTs cannot be actuated to pull-in (switch ON) state by conventional mechanical shocks in range of 10 1000 g under one-step voltage.
In the switch ON state, no significant insertion loss variations or problems in the contacts, due to the RF power, can be observed below 31 dBm input power.
In this electrochemiluminescence resonance energy transfer (ECL-RET) approach, Fe3O4@SiO2/dendrimers/QDs exhibited amplified ECL emissions (switch "on" state) and with the hybridization between T-rich ssDNA(S1) immobilized on the Fe3O4@SiO2/dendrimers/QDs and AuNPs modified with complementary aptamer (AuNPs-S2), the ECL of QDs nanocomposites was efficiently quenched (switch "off" state).
In the presence of Hg2+ ions, formation of strong and stable T-Hg2+-T complex led to the release of the AuNPs-S2 from double-stranded DNA(dsDNA) and the recovery of the ECL signal of QDs (second signal switch "on" state).
Table 1 Description of states Value Description 00 Going from state 0 to state 0 (switched OFF) 01 Going from state 0 to state 1 (switching ON) 10 Going from state 1 to state 0 (switching OFF) 11 Going from state 1 to state 1 (switched ON).
The simulated result demonstrates that the threshold acceleration (aths) under stable switch-on state is about 288 g and the contact time is about 198 μs when the pulse width of acceleration loads is 1 ms.
In eq.(1), Δt is the integration step, U Ci (t) is the voltage of SM capacitor, U Ci (t − Δt) is the SM voltage in previous integration, S Ci is a signal function with values of 1 and 0, which represents switch-on state and bypass state of SM, I SMi is the arm current flowing into SM.
The data samples were collected every 20 min up to 5 hr in five independent experiments for the switch-on state, and every 10 min up to 3 hr in four independent experiments for the switch-off state.
