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The switch to production mode is trigged by inducer addition, allowing yield, titer, and productivity to be managed through induction time.
In the Lepidoptera, for example, larval epidermal cells change their cuticle secretion program at metamorphosis and switch to production of pupal and subsequently adult cuticle.
The same DNA containing immune complexes may activate TLR 9 in DNA-reactive B cells to promote their survival through tolerance checkpoints and to help them class switch to production of the proinflammatory IgG isotype.
The observed exponential increase in enzymes for the specific carbon source followed by an abrupt switch to production of general growth genes is a solution of an optimal control model, known as bang-bang control.
We also confirmed the results obtained for in vitro analyses of human tissues, with telomerase activation involving the induction, or a switch to production of the full-length hTERT mRNA, as shown in various tissues [ 31- 34].
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That year Petronas was given exclusive rights to the nation's hydrocarbons; it forced the foreigners to switch to production-sharing contracts while it learned the ropes from them.
In her late teens she switched to production and personal assistant jobs, working for Bobby Darin, the Smothers Brothers, Henry Mancini and Norman Lear.
In mucinous carcinomas, there is a switch to the production of gel-forming mucins, products of the MUC2 and MUC5 genes (O'Connell et al, 1998).
If the product is successful they can switch to mass production.
Grains, wool, and meat were brought to New Hampshire cheaply, which forced farmers to switch to the production of such perishable items as dairy products, fruits, and vegetables.
Incorporating gene regulation into the model of solvent production by C. acetobutylicum enables an accurate representation of the pH-induced switch to solvent production to be obtained and theoretical investigations of possible synthetic-biology approaches to be pursued.
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