This is a mathematical formalism that also happens to be the foundation upon which the entire digital world has been built, ever since Claude Shannon showed more than half a century ago how to use simple analog switches to perform binary computations.
In some circumstances, people interact with a virtual keyboard by triggering a binary switch to guide a moving cursor to target characters or items.
Together, lines and bowl act as a binary switch to generate a stable Notch signaling interface between Dl-expressing cells and adjacent distal cell.
The {broad} placeholder represents a binary switch to change MACS's behavior between broad peak and narrow peak calling.
Therefore, Prospero acts as a binary switch to repress the genetic programs driving self-renewal (by directly repressing neuroblast transcription factors) and to promote differentiation.
We believe a similar logic can be applied to binary switch domains; for instance, an effector molecule (that is, heterochromatin protein 1) recognizing methylation on H3K9 would engage in competitive binding against another effector molecular recognizing a phosphorylation on H3S10 [ 41].
For this purpose, the gene expression values for switch-like genes were converted to binary values corresponding to the high and low modes of two-component distribution.
Thus, maintenance of presynaptic varicosities seems to be subject to a binary switch, and this suggested to us that loss of ptrn-1 might result in initiation or transmission of a retraction signal.
To produce natural speech, the fingertip switch produced binary commands of voicing and accent and the controller implemented the pitch generation model using the commands.
