Sentence examples for switch to activate the from inspiring English sources

This last hydrogen bond stabilised the helix and acted as a molecular switch to activate the transcriptional activity of PPARα.

Interestingly, Epe1 encodes a tyrosine in its active site that in vertebrate KDM7C has been shown to act as a phosphorylation-dependent switch to activate the enzymatic activity of KDM7C [ 80, 167].

The headlights and instruments are always lighted, but at night you must remember to click the light switch to activate the taillights — an electrical idiosyncrasy (for a 2008 car, anyway) that I learned about thanks to a helpful local constable.

When an explosion and fire crippled the deepwater drilling rig on April 20, workers threw a switch to activate the blowout preventer, which is designed to seal the well quickly in the event of a burst of pressure.

After Notch binding to the ligand and receptor proteolysis, the nuclear NICD interacts with RBP-Jκ/CSL through a conserved WxP motif in the Notch Rbp-associated molecule (RAM) domain, thus triggering the 'transcriptional switch' to activate the gene expression (Tamura et al., 1995).

Riboswitches sense the presence of specific metabolites and harness their conformational switching to activate the gene-control mechanisms in preventing the production of protein [12, 13].

For Turntable 2 (from the pre-recorded greeting card), you'll need the momentary switch to activate audio recording and the potentiometer for sound alteration.

But they claim that by using a metal collapsing dome (the part that must be pushed down fully to cause the switch to activate) and an "elastomeric spacer", combined with the natural resistance of the metal lever the user bending, they are able to provide a comfortable tactile experience while still losing a millimeter or two off the depth.

The PRDM12 gene, however, plays a key role in modifying a protein called chromatin which becomes attached to the DNA of the chromosomes and acts as a control switch to activate or deactivate other genes on the chromosome.

A reference on the very first page – "Pressing a make-believe switch to activate my imaginary lightsabre" (apparently in the year 'AD 2164', when spaceships can tunnel vast intergalactic distances through 'wormholes', the Star Wars franchise is still a going concern) – introduces a whole host of sly nods and winks.

In both, Drosophila and mammalian cells, the presence of NotchIC enhances RBP-J occupancy and irrespective of active repression by RBP-J or not, the binding of NotchIC to RBP-J mediates the transcriptional switch to activate gene expresssion from target promoters.