Your English writing platform
Discover LudwigExact(6)
The proposed protocol adopts the channel switch sequence (CSS) mechanism to cope with the channel collision problem and to reduce message exchange overhead for switching channels.
The switch sequence was employed by Pei and co-workers and by Bayley and co-workers.
These results indicated that administrating this system through a retrovirus successfully integrated the molecular switch sequence into target cells.
Following successful V(D J recombination, Ig heavy chain transcription runs through the variable domain, the IgM switch sequence, and the IgM and IgD constant regions.
To determine integration of the molecular switch sequence, a genomic extraction of NIH3T3 cells was collected and analyzed by nesting PCR.
Downstream of the Ig heavy chain J segments is a set of constant domains, each preceded by a several kilobases-long CSR target region termed a class switch sequence [ 12, 13].
Similar(54)
Inclusion of switch sequences provided a useful internal control and point of reference for interpreting the homology directed deletions.
This appears to occur not only at the switch sequences and variable domains of the Ig loci, but also at some pathologic locations, such as some oncogenes like c-myc [ 3, 4].
Most diagnostic labs have already invested in the optimization of PCR assays for the genomic regions of interest; it is therefore problematic to perform this optimization again in order to switch sequencing platforms.
This has a 5'P and 3'OH; CSR: class switch recombination; Class switch sequences or regions: repetitive units of length 25 to 80 that compose the class switch recombination regions in mammalian B cells; ALL: acute lymphoblastic leukemia or lymphoma.
For the aperiodic case, a new approach is proposed to construct switching sequences, and the number of switchings involved in each designed switching sequence is shown to be upper bounded by d(d−d1+1).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com