Sentence examples for switch off genes from inspiring English sources

Yet many mutations switch off genes or make products that do nothing at all.

These mutant stem cells also fail to efficiently switch off genes that stop stem cells from becoming more specialized.

Other mice had a mutation in a domain of the protein that works to switch off genes.

Previous work conducted in 2010 reported that mice could be genetically engineered to produce short stretches of RNA molecules that can switch off genes from the foot-and-mouth disease virus.

As described above, β-myrcene stimulus activates specific pathways on Pseudomonas sp. M1, which in turn appears to switch off genes that might become a metabolic burden for growing cells.

The positioning of nucleosomes on the DNA (regulated by chromatin remodelling complexes) and the higher order structure of the histone octamer core (controlled by acetyl transferases and deacetylases) facilitate stochastic access for transcription factors to bind promoter regions, or methylases to switch off genes epigenetically.

Such terminal differentiation and transitional stages between nucleated and enucleated cells must imply not only an important rearrangement of the nucleus but must also implicate a large-scale genome reorganization designed to switch off gene expression that is no longer required.

Therefore, targeted DNA methylation can provide a unique opportunity to heritably switch off gene expression (loss of function) [ 37- 39].

Xist recruits the polycomb repressive complex 2 (PRC2) to switch off gene expression from one X chromosome in each female cell [45].

However, this approach needs further research if we are to unravel the changes that occur in these lymphocytes and to develop the capacity to switch off gene expression or destroy the lymphocytes in case of an adverse event.

Switching off genes in mice to study human diseases is a standard technique.