Sentence examples for swift activation from inspiring English sources
Swift activation of leucocytes is important for an adequate immune response.
Swift activation of NKDCs following α-GC-mediated activation of NKT cells suggests that NKDCs might respond directly to cytokines that are immediately released by activated NKT cells.
Mitogenic stimulation with PMA and ionomycin ensures a strong simultaneous and swift T-cell activation circumventing the upstream T-cell receptor signaling, thereby allowing efficient triggering of its downstream signaling events, including activation of protein kinase C and triggering of Ca2+ influx, both of which are known to increase FOXP3 binding to genomic DNA [ 6, 19].
For example, tissue injury can trigger protease activities, leading to a rapid release of signaling molecules [such as transforming growth factor-β (TGFβ) (Wipff et al., 2007; Wells and Discher, 2008)], which in turn allows a swift and local growth-factor-mediated activation of cellular functions without de novo synthesis.
This exquisite level of regulation may have evolved to allow swift responses to various cellular stresses, for example, to safeguard against inappropriate activation of cell death or enhance cell death, depending on the cellular context.
It is likely that activation of the pathways centered on these counter-regulatory circuits is more swift and crucial in the context of an ischemia and reperfusion (I/R) injury, often referred to as "inflammation from within" (8).
It is supposed that a swift and strong expression level of IL-6 mRNA induces migration of PMNs and triggers the activation of transcription including TNF-α and IL-1β.
Insights into T cell activation and tumor suppressor-dependent changes of glycogene (glycosyltransferases, lectins) expression, for instance, have exemplified how swift reprogramming of distinct aspects of the glycophenotype elicits growth regulation [ 4- 11].
"It's an activation device".
