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FDOCT can be realized in two ways, either through the use of a broadband source and spectrometer (spectral-domain, or SDOCT) or a frequency swept laser and high bandwidth detector (swept-source, or SSOCT).
Recently, a new swept laser source technology was developed based on MEMS-tunable vertical cavity surface emitting laser (VCSEL) [ 37].
Figures 2(a) and 2(b) show a schematic of the VCSEL swept laser (Praevium Research, Inc. and Thorlabs, Inc).
In SS-OCT, axial scan rates are given by the repetition rate of the wavelength swept laser.
Klein et al. demonstrated an FDML-type swept laser at a 1.37 MHz A-scan rate [ 17].
Bonin et al. used a swept laser as the source of a full-field OCT system using an area CMOS camera for frame detection.
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Short cavity swept lasers, with few centimeter cavity lengths, also enable high sweep rate operation [ 36].
Several implementations of swept lasers have been described in literature such as mechanical scanning [ 4– 7], tunable filtering of fiber ring lasers [ 3] and Fourier domain mode locking (FDML) lasers [ 8].
Although the limited detector bandwidth along with the limited coherence length of the swept source laser used in this paper affected signal in the rat retina during full eye length imaging (Fig. 4B Fig. 4C), next generation swept lasers with ultralong coherence lengths will have virtually no signal roll-off within the range needed for rodent full eye length imaging [ 28].
The swept source laser design employed a buffered polygon ring cavity laser.
The swept source laser design is a buffered polygon ring cavity laser where a 600 lines/mm diffraction grating (GR25-0613, Thorlabs) was chosen to create the necessary dead time between laser sweeps to enable buffering from 54 kHz to 108 kHz [ 19].
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