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Here we evaluate a methodology for swapping module specificities of these mega-enzymes that takes advantage of flavodoxin-like subdomains involved in substrate recognition.
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"With Blocks you can upgrade your smartwatch and tailor it to suit what you need it to do at that moment, just by swapping out modules".
So the concept of swapping certain modules in or out might end up being eclipsed by the rising capabilities of rival devices.
Because C domains have been shown to have non-negligible specificity for the amino acid that is activated by the downstream A domain, swapping whole modules or insertion/deletion seems to be more promising, provided that the integrity of the functional domains is carefully maintained and the modules are dissected in their linker regions [ 8, 9].
Two new recombinants of avermectin polyketide synthases were constructed by domain and module swapping in Streptomyces avermitilis 73-12.
Over time the attackers swapped out modules that didn't work and replaced them with new ones perhaps as Stuxnet made its way to its intended target.
But a smartwatch still needs to be robust enough to withstand daily wear and tear — so the mechanism for securing and swapping out the modules is a very vital link in the chain here.
To streamline the construction and optimization of synthetic retrotransposons, we have implemented a highly efficient modular design for L1 vectors allowing "plug and play" swapping of individual modules as new knowledge is gained and optimization of constructs proceeds.
Try it on practice greens, and if you want to take the putter on the golf course and abide by the rules, you can swap the digital module for a plain module without the technological advice.
Google also hopes to double the number of modules available for swapping in and out when it brings out Spiral 3 later this year.
Project Ara's success will depend largely on developers and companies embracing the product's upgradable nature that includes packaging different components like the camera, processor and battery in blocks that can be swapped for different modules.
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