Due to high diversity in the sequence, structure and functions of proteins involved in domain swapping, availability of such an algorithm to predict swapping events from sequence and structure-derived features will be an initial step towards identification of more putative proteins that may be involved in swapping or proteins involved in deposition disease.
Hinting at a lobbying campaign to come, Robert Pickel, the chief executive of the International Swaps and Derivatives Association, a trade group, said his organization "looked forward to working with policy makers to ensure these reforms help preserve the widespread availability of swaps and other important risk management tools".
Another is the possible negative impact of credit-default swaps on the cost and availability of debt for California, a worry shared by corporate borrowers.
Other studies have found that including the availability of reserves, or ability to swap reserves for more favorable ones, in the future can increase the efficiency of conservation [20], [21].
"Via the app the employee receives messages, notifications and reminders, and they can easily communicate and swap shifts with co-workers with matching skills and availability.
They have asked about the availability of hitters like Houston's Daryle Ward and could try to swap for Tampa Bay's Fred McGriff, knowing that McGriff could exercise his no-trade provision and void any deal.
Since proteins involved in the 3D domain swapping phenomenon play a prominent role in the structural, functional and regulatory aspects, future versions of 3DSwap will be released periodically, depending upon the relative availability of a significant number of structural entries with 3D domain swapping in the PDB.
The availability of the pK18mobsacB plasmid [16] for constructing serial gene deletions, insertions and swaps allows extensive reconfiguration of bacterial genomes.
We envisage that the availability of the 3DSwap database, with its curated content and information related to domain swapping, will be one of the most useful resources for the research community interested in studying 3D domain swapping in great detail.
