Sentence examples for sustains the expression from inspiring English sources

We show that the IKKβ-NF-κB cascade sustains the expression of anti-oxidant genes and that inactivation of this cascade impedes the scavenge capacity and results in ROS accumulation.

Activin signaling sustains the expression of pluripotency-associated genes such as nanog and inhibits BMP signaling, which promotes self-renewal in human embryonic stem cells [ 112].

The IL-12Rβ2-expressing T cells can then directly respond to IL-12 that, through activation of STAT-4, induces high IFNγ production and sustains the expression of IL-12R β2 [ 15].

Fourthly, NeuroD6 sustains the expression of the transcriptional co-activator PGC-1α and the nuclear-encoded transcription factors Tfam and NRF-1, all of them known to regulate mitochondrial biogenesis.

FGF2 sustains the expression of Nanog (a pluripotency marker) and this sustained Nanog expression is found to shift the outcome of BMP4 induced differentiation of hESCs towards mesendoderm [ 22].

The most well characterized of the SET1 proteins is MLL1 (hereinafter referred to as MLL), a key developmental protein that sustains the expression of selected target Hox genes required for proper embryonic development including the haemopoietic system [ 4], myogenesis [ 5] and neurogenesis [ 6].

This is in marked contrast to the inability of IL-2-deprived T cells to sustain the expression of endogenous or ectopically expressed retroviral wild-type Myc (Fig 3D).

These data show that in the absence of IL-2, CTL cannot sustain the expression of Myc from endogenous or ectopically expressed retroviral Myc transcripts.

EMT process ongoing in embryogenesis is named Type I and Type II is linked to regeneration/fibrosis). OPN is able to bind different integrin receptors and several transcription factors regulated by TGFβ sustain the expression of OPN.

Therefore, menin was dispensable for the initiation of the heat shock response but was required to sustain the expression of heat shock protein genes.

A PcG gene, Rae28, has previously been shown to be required for sustaining the expression of the cardiac selector gene Nkx2.5 in developing mouse embryos [47].