Thus a small decrease in glucose availability may render these cells incapable of producing sufficient energy to sustain their function and lead to cell death.
With fewer, larger neurons per gram of tissue, whether or not accompanied by decreased average firing rates, larger brains would need smaller amounts of energy per gram of tissue to sustain their function.
A distinguishing feature of TICs is their self-sufficiency and their use of specific signalling pathways to sustain their function (DiMeo et al, 2009; Fillmore et al, 2010; Ginestier et al, 2010; Kim et al, 2012a; Korkaya et al, 2011; Marotta et al, 2011; Sansone et al, 2007; Scheel et al, 2011).
Are specific cell types released from the BM 'ready-made' and successively recruited to the ischemic limb, or are their receptor expression and downstream signalling altered once the cells encounter the ischemic area, thus helping them to engraft, survive, and sustain their function?
Although differentiated neurons have relatively stable morphologies, they nevertheless undergo dynamic structural changes in order to sustain their functions.
In criticizing tenure, John M. McCardell Jr. ignores an important virtue of the system: tenure makes academic citizens of the faculty, sustaining their role in the very functioning of the university.
In order to sustain their religious function, Tibetan wall paintings were always repainted even when they were only partly damaged.
Many tissues are comprised of multilayered structures for which spatial organization and inter-layers cellular communications are essential to sustain their biological functions.
The mitochondrion is the main intracellular site of energy production and is the evolutionary response to the main challenge that living organisms have to face: gaining energy from their environments to sustain their biological functions.
The core of Evo-Devo lies in the intuition that the way tissues grow during embryonic development, the way they sustain their structure and function throughout lifetime, and the way they evolve are closely linked.
