Sentence examples for sustaining the stem from inspiring English sources
The p63 knockout mice show severe skin defects (Mills et al, 1999; Yang et al, 1999), and remnant cells on the defected skin express terminal differentiation markers (Yang et al, 1999; Yang and McKeon, 2000), indicating physiological roles of p63 in sustaining the stem cell population and regulating differentiation of the epidermis.
In this way, auxin signalling in the shoot meristem could sustain the stem cell pool required for future lateral organ formation.
We can conclude that early autophagy regulators, like Ambra1 and Beclin 1, on the one hand sustain the stem cell pool within the adult SVZ and, on the other hand, control the level of immature neurons by enhancing the survival of neural precursor cells.
As AKT and HIFs were shown to sustain the stem-like GSC phenotype, this warrants future studies to discover the interplay between IR, hypoxic signaling and AKT/survivin to install the GBM dedifferentiation process.
This evidence confirmed our hypothesis and suggests a prominent role of Pin1 in sustaining the mammary stem cell compartment in vivo.
Thus, overall, autophagy could be important in the survival of ANSCs, controlling ANSCs'stemnessss' and sustaining the pool of stem cells in the SVZ niche.
In addition, TAZ endows self-renewal capability of breast cancer cells to sustain the cancer stem cells population (Cordenonsi et al., 2011).
As coexpression of CD44 and CD133 was not detected in these pools of cells, it appears that CD44 is not essential for sustaining the pool of cancer stem cells.
In contrast to the ongoing controversy with regard to the possibility of ongoing renewal of oogenesis in the ovary and the possible existence of oocyte-producing stem cells in the adult ovary, the existence of stem cells sustaining the other compartments of the ovary has long been neglected.
This gives rise to a hierarchical clonal stem cell disease often with more than one expanding leukemic stem cell (LSC) population sustaining the malignancy, with the BM being the primary site of disease development.
