Sentence examples for sustaining stem cell from inspiring English sources

Depending on the concentration of ATP in the extracellular milieu, it can act by sustaining stem cell proliferation (Aa in Tab. 3 of mathematical model), by leaving stem and progenitor cells in a resting state (Ai in Tab. 3) or by killing SVZ cells and neurons (excitotoxicity).

Indeed, EZH2 can directly methylate the promoters of transcription factors that are essential for sustaining stem cell pluripotency [ 8].

These experiments demonstrate the overarching importance of the signals provided by mammary epithelial cells for the development of a microenvironment(s) capable of sustaining stem cell activity and differentiation.

Therefore, these results indicated that Oct4 plays a critical role in sustaining stem cell self-renewal and that up- or downregulation of Oct4 expression induces divergent developmental programs, suggesting that Oct4 is the master regulator of pluripotency and that it may also control lineage commitment during early embryonic development [ 14].

B-MYB is therefore critical to the establishment of inner cell mass through cell cycle progression and is vital in sustaining stem cell populations and self-renewal capacity, two vital factors in the maintenance of tissue function, and thus healthy aging.

Let me be clear: if we want to sustain stem cell research and bring new cures and treatments to millions of people, I believe admixed embryos are necessary.

However, graphene and its derivatives [graphene oxide (GO), and reduced graphene oxide (rGO)] have all shown to induce and sustain stem cell growth and differentiation with considerable efficacy, while being capable of enhancing osteogenic differentiation [22].

Interestingly, it has been shown with mouse embryonic cells that Id proteins, such as Id3, in conjunction with STAT3 sustain stem cell self-renewal and inhibit differentiation[56].

Thus, a critical amount of Oct3/4 is required to sustain stem cell self-renewal, and up- or downregulation induces divergent developmental programs.

Second, the transcription factor, Oct4, is able to encode two functional isoforms, Oct4A and Oct4B, whereas only the Oct4A isoform is able to sustain stem cell properties [ 26].

Id1 sustains stem cell phenotype as it controls the expression of Sox2, responsible for stem cell self-renewal, and promotes cadherin switching, which has been associated to epithelial mesenchymal transition.