The rapidly declining plasma glucose resulted in insufficient glucose delivery to the brain to sustain normal functions.
Operational failure of the normal immune regulatory mechanisms in the ovary and its draining lymph nodes, particularly loss of immune suppressive regulatory T cells (Treg cells), may be instrumental in causing premature ovarian insufficiency in some women (48), demonstrating the key role of Treg cells in sustaining normal follicle function.
25 Under normal conditions, basal endogenously generated NO, produced via the conventional l-arginine/NO synthase (NOS) pathway is essential for maintaining homeostasis, particularly, by sustaining normal healthy cardiac function, perfusion and cardioprotection.
Imperative for the success of such an endeavor will be the ability to identify compounds selective for Cav2.2, versus other VGCCs, but also compounds which demonstrate effective blockade during the pathophysiological states of neuropathic pain without compromising channel activity associated with sustaining normal housekeeping cellular functions.
Until now, in vitro BBB models have focused on investigating the interplay among cellular components of neurovascular units and the effect of fluidic sheer stress in sustaining normal BBB phenotype and functions.
Episodes of hypoglycaemia are distressing, either because of the symptom response to the falling blood glucose concentration, or because of the alteration in brain function that occurs if the plasma glucose falls too low to sustain normal neuronal function.
In order to sustain normal cellular function, therefore, the mitochondria require a constant supply of fuels and oxygen.
Three of them exhibited hepatic dysfunction and two of them showed sustained normal liver function during chemotherapy.
We disagree with this determination because even with a complete inhibition of thyroidal iodine uptake, the amount of iodide stored in an iodine-replete adult can sustain normal thyroid function for several months (Greer et al. 2002).
The expression of multiple proteases in P. marinus may indicate their role(s) in processing the host protein substrates to facilitate uptake of their metabolic products to sustain normal cell function and proliferation.
