Sentence examples for sustaining expression of from inspiring English sources

21 Claudin-3 and -4 control tumor growth and metastases by sustaining expression of E-cadherin and limiting β-catenin signaling.

The observation that BMP caused pluripotent cells to remain epithelial by sustaining expression of E-Cadherin led Malaguti et al. to hypothesize that this protein could be the key factor downstream of BMPs in pluripotency.

Three out of the four HCpro mutants suppressed RNA silencing more efficiently and sustained expression of co-expressed jellyfish green fluorescent protein for a longer time than wild-type HCpro in agroinfiltrated leaves of Nicotiana benthamiana.

Cancer cells that express oncogenic alleles of RAS typically require sustained expression of the mutant allele for survival, but the molecular basis of this oncogene dependency remains incompletely understood.

As a result, the sustained release of DNA from modified foams led to negligible cytotoxicity and sustained expression of DNA which is favorable for DNA delivery and tissue engineering application.

Both of these properties are crucial for achieving sustained expression of the transgene.

Lentiviral vectors transduce both dividing and non-dividing cells and can support sustained expression of transgenes.

Seiler, M.P. et al. Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling.

Such long-term survival represents an important first step toward developing an optimal cell-based delivery system that generates sustained expression of a therapeutic molecule.

However, long-term, high-level, and sustained expression of angiogenesis inhibitors, such as angiostatin, is necessary to prevent dormant tumors from becoming active again.

Limiting the lethality inherent in the Sindbis virus vector in order to enable long term, sustained expression of recombinant proteins may be possible.