Sentence examples for sustaining expression from inspiring English sources

21 Claudin-3 and -4 control tumor growth and metastases by sustaining expression of E-cadherin and limiting β-catenin signaling.

The observation that BMP caused pluripotent cells to remain epithelial by sustaining expression of E-Cadherin led Malaguti et al. to hypothesize that this protein could be the key factor downstream of BMPs in pluripotency.

We show that the protein kinases NIK and SMG1 have important roles in protecting cancer cells from SMC-mediated TNF α-induced apoptosis, likely through sustaining expression levels of c-FLIP that corresponds to the long isoform.

It is possible that post-translational modification may influence specific trafficking (13, 14), but the extent to which intrinsic features of the two proteins, or different cell types sustaining expression, are responsible for different trafficking patterns is not clear.

With the experiments reported here, we have obtained heterologous expression of ATP7A and ATP7B in the same mammalian cell line (COS-1) infected with adenovirus vectors and characterized features pertinent to each protein expressed in the same cell type, in a manner independent of extrinsic factors that may be related to different cell types sustaining expression.

We used heterologous expression of ATP7A or ATP7B in COS-1 cells infected with adenovirus vectors to characterize differential features pertinent to each protein expressed in the same mammalian cell type, rather than to extrinsic factors related to different cells sustaining expression.

Three out of the four HCpro mutants suppressed RNA silencing more efficiently and sustained expression of co-expressed jellyfish green fluorescent protein for a longer time than wild-type HCpro in agroinfiltrated leaves of Nicotiana benthamiana.

Cancer cells that express oncogenic alleles of RAS typically require sustained expression of the mutant allele for survival, but the molecular basis of this oncogene dependency remains incompletely understood.

Fkbp9 (FK506 binding protein 9) is strongly expressed in the megakaryoblastic leukaemias with a weaker but sustained expression in other types of leukaemias.

As a result, the sustained release of DNA from modified foams led to negligible cytotoxicity and sustained expression of DNA which is favorable for DNA delivery and tissue engineering application.

Both of these properties are crucial for achieving sustained expression of the transgene.