My journey in medicine has taken me through institutions where anesthetized surgery was first performed and the life sustaining agent used to save countless premature infants, surfactant, was discovered.
In addition, the present data, together with our previous observations and the data present in the literature, strongly persuade us that ALR not only supports cell survival by its anti-apoptotic effect but also holds the crucial function of an anti-oxidative agent sustaining the levels of reducing agents such as clusterin.
These novel copolymers, thus, act as both nanoscale gene delivery vectors and macroscale sustained delivery agents, and make a clinically viable long-term sustained gene delivery system.
Let us also consider that certain microbes are likely to account for chronic (inflammatory) diseases that are specifically human, as starter or sustained etiological agents.
However, such cooperation of hub agents was sustained by the neighbor agents in a non-cooperative strategy.
The dissolution rate of nitrendipine from microspheres was enhanced significantly with increasing the amount of dispersing agents, and sustained by adding retarding agents.
Yet even after two decades as a novelist she clearly remembers some of the downsides of acting: getting and keeping agents, difficulties sustaining a career.
In addition to standard non-pharmacotherapeutic modalities, the use of anti-inflammatory agents, adjunctive analgesics, or long-acting (e.g., methadone) or sustained-release opioid agents (e.g., morphine ER) were preferred.
Under the assumption that agents remain in the system for significant time periods, or that the agent composition changes only slowly, we have previously presented a prescriptive strategy for promoting and sustaining cooperation among self-interested agents.
Moreover, the liposome could sustain releasing antitumor agents so as to extend action time, improve drug efficacy, and decrease adverse reaction [25].
