Sentence examples for sustaining a functional from inspiring English sources

Therefore, if reduced heterochromatin is also found at the centromeres of undifferentiated hPSCs, this unique chromatin architecture may create the opportunity for sustaining a functional centromere under circumstances where CENP-A protein levels become significantly reduced.

One of the possible subjects to be solved using this advance of data is the identification of a minimal gene set i.e. an estimation of the genes that are necessary and sufficient for sustaining a functional cell under certain conditions [ 1].

This gain-of-function BubR1 mutant cannot sustain a functional checkpoint.

This was enough to sustain a functional structure for the vaccine.

Elysia's genome contains at least one algal gene, and while more could lie in wait, it's unlikely to contain the hundreds necessary to sustain a functional chloroplast.

We recently showed using a cell culture model of acute mitochondrial DNA (mtDNA) depletion that electron flow sustains a functional oxidative TCA cycle, which in turn is necessary to maintain histone acetylation in the nucleus.

In the end, LGUs will be supported to develop, strengthen and sustain a functional service delivery network for mothers and children.

Gil et al. [ 13] used a consensus strategy integrating different types of information as well as previous minimal gene sets to define the core of a minimal gene set "able to sustain a functional bacterial cell under ideal conditions".

This hypothesis would only be plausible if heterochromatin were not necessary to sustain a functional centromere, and indeed this was recently shown using neocentromeres as a model in lymphoblast and fibroblast BBB lines (49).

Based on our finding that macromitophagy plays an essential role in preserving the mitochondrial network in CR yeast, we hypothesized that this form of selective macroautophagy is required for sustaining a healthy population of functional mitochondria in chronologically aging cells.

It has been argued that most brain functions commonly cited as integrative merely sustain an existing functional integration, suggesting that the brain is more an enhancer than an indispensable integrator of bodily functions (Shewmon 2001).