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GDF6 is nearly exclusive to P5 RPE cells and as such it is a candidate ligand for mediating the irreversible switch in phenotype following sustained wound stimulus.
Liver fibrosis and its end-stage, cirrhosis, result from a sustained wound healing response to chronic or repeated injury, leading to formation of scar tissue, loss of tissue architecture and organ failure.
Fibrosis and cirrhosis represent the consequences of a sustained wound healing response to chronic liver disease induced by a variety of causes, including viral, autoimmune, drug-related, cholestatic and metabolic damage.
Specifically, the information collected was related to the number of: HCWs, needle-stick injuries, sustained wound cuts with a sharp object, non-intact skin exposures, mucous membrane exposures (splashes), and bite injuries resulting in blood exposure to either person involved.
Here, we have shown that when RPE cells are subjected to sustained wound stimulus by impairing the establishment of cell-cell contacts, there is a self-perpetuating activation of TGFβ pathway that persists even after a confluent monolayer is reestablished.
Similar(55)
"Along with this, three policemen died and five sustained wounds of various seriousness".
A passer-by, Hussam Shadhan, 36, sustained wounds to his hands in the explosions.
Mr. Dogan sustained wounds to the face, back of the skull, back and left leg.
About half sustained wounds that turned green; the other half were affected by skin loss and weeping blisters.
The 35-year-old teacher sustained wounds to his back and one hand in the incident near the Franco-Hebraic Institute on Monday.
The gunman left Pastor with injuries to her face, neck, chest and abdomen, while Darwish sustained wounds to the face, neck and stomach.
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