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We repeated these experiments using unpolarized, immortalized adult lung-derived HBE cells and observed transient induction of ERK1/2 by FGF-10, which was not sustained with time or increased FGF-10 dosage (Supplemental Figs. S4 and S5).
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However, salivary gland cancer had the greatest SIR values and sustained risk with time: even after 10 years, a high relative risk was still present; SIR 15.3 (7.29–32.1) before 1 year and SIR 4.7 (1.18–18.8) after 10 years.
However, Salazar's insistence on maintaining Portugal's colonies in Africa could only be sustained with difficulty at a time when the other European colonial empires in Africa were being dismantled.
Studies suggest that the presence of C. difficile in the natural environment is transient with recovery of the strains variable between sites and time, but sustained with the species present at sites across a location (Zidaric et al. 2010; Higazi et al. 2011; Hargreaves et al. 2013).
In the first study, simulated data were produced with sustained time courses, transient time courses, and the sum of both together.
Thereafter, the expression profile of mfc1 + was relatively sustained with only a slight decrease over time being observed.
This effect may need to be sustained, with higher frequency of zoledronic acid administration, over a longer time period.
In the meantime, the life of Watermill is a bustle of intense creative activity, driven in no small measure by the obvious delight of his collaborators at having rare sustained time with him.
The most promising approaches are those designed with input based on extensive formative research including studies with youth, directed at multiple levels of the social ecology, and sustained over time with significant resources and ongoing, multi-sector inputs.
One of Berry's former minor league teammates, Domonic Brown, is now getting his chance for sustained playing time with Phillies, who traded the veteran outfielders Shane Victorino and Hunter Pence last week.
However, such provisions need to be done regularly and sustained over time, with depth and are embedded in teachers' day-to-day teaching life (Desimone, 2011; Hairon, 2008).
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