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In the phase II clinical trial, subjects randomly assigned to tramiprosate demonstrated sustained safety and tolerability as well as a reduction in CSF Aβ42 levels [ 47].
13– 17 Recently, several trials have addressed the concern of long-term safety and efficacy of botulinum toxin type A and these found sustained safety and efficacy after repeated administration of the neurotoxin.
Sustained safety results for LCA [ 9] have led to a phase III clinical trial at the University of Pennsylvania, which is currently recruiting children (clinicaltrials.gov: NCT00999609).
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The nuclear power industry has a compelling history of improving and sustaining safety from which healthcare could learn.
This W nanolayer application showed improved electrochemical properties and sustained structural safety.
The next generation of outcome analyses will indicate whether the benefits are sustained as Safety Counts is adopted at the local level.
31 Therefore, whether cobalt-chromium everolimus eluting stents would provide sustained improved safety over bare metal stents and most importantly to what extent this could translate into an improved survival rate remains so far largely elusive.
"But for the short term, states need this bridge to sustain the safety net of human services programs and education".
Current evidence sustains the safety of the use of thimerosal as a preservative for inactivated vaccines [66].
Capital requirements of food safety systems increase the demand for scarce funds, and public-sector credit support may be needed to jump-start and sustain food safety systems.
This collaborative may serve as a model to implement feasible and methodologically rigorous methods to improve and sustain patient safety on a larger scale.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com