Your English writing platform
Discover LudwigExact(14)
Biomaterials capable of providing localized and sustained presentation of bioactive proteins are critical for effective therapeutic growth factor delivery.
However, most previous studies on this were limited to using high spatial frequencies, sustained presentation, and criterion-dependent methods for assessing threshold.
Experiment 3 explored whether similar local biases occur during sustained presentation of a continually moving target.
Early works on rivalry dynamics (for a review, see [14]) usually focus on the alternating perception during sustained presentation of rivalry stimuli (Figure 1A).
Very recently, the ability of the C-glycoside to stimulate a Th1-polarized response following iNKT cell activation has been attributed to its more sustained presentation compared to KRN7000, despite the finding that iNKT cell TCRs showed a much lower binding avidity to complexes of C-glycoside bound to mCD1d [27].
10.7554/eLife.06994.007 Figure 4. 200 nm particulate antigen challenge promotes sustained presentation of peptide/MHCII by dendritic cells (DCs).
Similar(46)
This effect is largely owing to the collagen-binding domain that serves to sustain presentation of EGF toward cells within the hydrogel.
Thus, increasing particle size, and sustaining presentation by DCs and their cognate interactions with T cells underpins the success of the larger particle in driving Tfh differentiation.
Possible explanations for this difference are increased inflammation and more sustained antigenic presentation during infection.
Indeed, sustained antigen presentation associated with Tfh induction has been reported in the absence of cognate interactions with B cells (Deenick et al., 2010).
While only a brief period of activation (24 48 h) is required to initiate proliferation of CD8 T cells (Kaech & Ahmed, 2001; van Stipdonk et al., 2001), sustained antigen presentation and inflammatory signals (>48 h) are required for robust CD8 T-cell expansinn in vivo (Prlic et al., 2006).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com