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IL-17 increased p53 expression prior to synoviolin expression at 4 h and 6 h respectively following IL-17A treatment which was sustained out to 24 h (data not shown).
Interestingly, this decrease was sustained out to 48 h, providing further evidence of the potent metabolic effects of this agent.
Four of the 195 patients died while on eculizumab treatment; the Kaplan Meier estimate of patient survival at 36 months was 97·6%[95%% confidence interval (CI), 93·7 99·1%], which was sustained out to 66 months (Fig 4).
Neutralizing antibody titres were sustained out to 16 weeks post vaccination, and, for comparable doses of vaccine, somewhat higher titres were observed with intracutaneous patch delivery than with intramuscular delivery with the needle and syringe at this time point.
In diabetes patients, 30 weeks of exenatide reduced mean HbA1c~11% with weight loss, effects that were sustained out to 3 years in open-label extensions [ 15, 16].
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The previous year the state's supreme court had ruled that out-of-state plaintiffs could sue out-of-state companies for injuries sustained out-of-state, so long as a company in West Virginia had sold or distributed the product alleged to have caused those injuries.
See related research by Kolar et al., In their report on 737 patients who sustained out-of-hospital cardiac arrest, collected over an interval of 9 years in a well-organized emergency medical system, Kolar and colleagues confirmed that the measurement of end-tidal carbon dioxide tension (PetCO2) is predictive of the outcomes of cardiopulmonary resuscitation [ 1].
Then there were the controversial back injuries that both Lindros and LeClair sustained working out together over the summer.
The band's most distinctive element is Ms. Lee's voice: high, strong and perpetually sustained, holding out every note of her long melody lines.
I had the long and shocking list of injuries the young woman had sustained, read out to him.
Importantly it is unlikely this knowledge could be readily gained from human studies as the sustained "all out" effort required to elicit such molecular responses is difficult to attain from untrained/sedentary human subjects, but is naturally achieved by Thoroughbreds.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com