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These included: (i) sustained modification of TG-rich lipoprotein characteristics, which were independent of the effect of alipogene tiparvovec on total TG levels; (ii) persistence of transgene expression; (iii) improvement of clinical symptoms as reported by the patients and (iv) reduced incidence and/or intensity of pancreatitis (Gaudet et al, 2012a, b).
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However, the repetition of tDCS sessions over 8 weeks could have been responsible for neuroplastic changes and induce sustained modifications within the underlying visual cortex.
Patients with hypertension are advised to lower their blood pressure to <140/90 mm Hg through sustained lifestyle modification and/or pharmacotherapy.
In our study, a moderate, but sustained, lifestyle modification and/or metformin produced similar beneficial changes.
Further study to identify effective parameters and explore the role of team leaders for sustained behavior modification in our setting is being undertaken.
The Treasury said on Wednesday that it had always anticipated that some homeowners would not sustain a modification, which was one reason the program had been greatly expanded.
In addition, they faced similar challenges in sustaining lifestyle modification (34, 37, 43).
However, several respondents commented about the difficulty of sustaining lifestyle modification over time.
In addition, questions over their ability to sustain behaviour modification, once an incentive is withdrawn, were raised [ 64].
It has previously been reported that an increase in growth rate requires Sam1p, and further increases results in yet more demand for methyl donors to sustain rRNA modification, also requiring higher levels of Sam2p, a close homolog of Sam1p [ 20].
Achieving and sustaining lifestyle modification for the prevention of diabetes, though efficacious [ 6] is challenging, and hence the potential role of optimal vitamin D status in reducing diabetes burden is attractive.
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