The results of our experiments demonstrate that septic animals sustained marked sepsis-induced myocardial dysfunction, as evidenced by significantly reduced baseline (d LVP and LVPmax compared to control animals, p = 0.0001 and p = 0.00003, respectively (Figures 1 and 2).
Were responses immediate or gradual, temporary or sustained, marked or modest?
This should not be surprising given that these subjects tend to have sustained and marked BP elevation, whereas white-coat hypertension is most common in subjects with BP close to the threshold for hypertension diagnosis.
Yet others argue that retail access restrictions are insufficiently comprehensive to have had a sustained or marked effect on behaviour, and claim investment in other tobacco control measures would provide better returns.
When patients developed sustained agitation, marked dyspnea, pulse oxymetry <88% for ≥5 minutes or arrhythmias, sedatives were restarted at one-half of the previous dose and then titrated to achieve the target sedation level.
It is uncertain whether the lack of gastrointestinal effects of DPP-4 inhibitors occurs because the resulting rise in peripheral active GLP-1 concentrations is not elevated or sustained, in marked contrast with concentrations observed during peripheral GLP-1 infusion.
Importantly, results from these clinical trials have confirmed pre-clinical data obtained in animal models, indicating low oncogenic potential of new generation LV in HSC, regardless of the sustained gene marking that is necessary to ensure therapeutic levels of transgene expression (35).
Just be careful not to bring the book into direct contact with the charcoal or it may sustain blackening marks.
Kitzinger's daughter, Tess McKenney, had a "wonderful" water birth with a first baby who was just as heavy as mine: "The only injuries I sustained were red marks where my back rubbed the side of the birthing pool").
The assembled lawmakers seemed less inclined to join in the usual stream of sustained, loud clapping that have marked past addresses given in the chamber.
