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Surprisingly, ERK activity was high and sustained in control SW480 cells throughout the culture in suspension but did not prevent the upregulation of Bim expression in control SW480 cells starting at 5 h.
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In the present study, time course EGF stimulation studies showed that EGF-induced Ras, ERK1/2, and Akt activation was suboptimal and short-lived in SHP2-silenced cells but robust and sustained in controls (Fig. 2a d).
While HGF- and FGF-induced ERK1/2 and Akt activation was suboptimal and short-lived in the SHP2-silenced cells, it was augmented and sustained in the controls (Fig. 6a d).
Mcl-1 and Bcl-2 expression was sustained in anoikis-resistant control cells cultured in suspension on poly-HEMA.
In the cultures with added anaerobic inoculum, H2 production was most sustained in the positive controls with glucose, where the pH was also the lowest.
At 105 min the PCO2 gap had increased by approximately 150% (P < 0.0001) in both groups (Fig. 2) and showed a sustained increase in control animals.
They will usually place their hand on top with their palm facing downwards; the grip will be firm and sustained in order to demonstrate control.[13].[13]
As malaria incidence falls, and it becomes increasingly important to identify the majority of infections to sustain progress in control [29].
As in HIV-infected individuals, though, this control is not sustained in the brain.
This effect refers to the results of a 10-year follow-up study to the United Kingdom Prospective Diabetes Study, which found that intensive glucose control in newly diagnosed T2DM patients provided long-term benefits on cardiovascular outcomes and mortality, even if intensive control was not sustained in the long term.
By contrast, in PA neurons, responses to higher level sounds were more sustained than in controls, and bursts were longer than at lower levels because post-burst inhibition was weaker.
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