Sentence examples for sustained in cells from inspiring English sources

As Figure 3a shows, AKT phosphorylation was sustained in cells lacking PTP1B.

In the present study, the expression of γ-H2AX was greatly increased and was sustained in cells upregulated with miR-207.

Compared to that of wild-type SHP2-expressing cells, the level of ERK1/2 phosphorylation was further elevated and sustained in cells expressing the GOF E76K mutant as well as the LS SHP2 mutants.

Therefore, receptor signaling may be sustained in cells in HOIL-1 KO mice, resulting in the increase in TNFα, IL-6 and IL-12, and ultimately IFNγ protein, observed in the serum of chronically infected mice.

However, we now show that this effect is not sustained in cells that are stably depleted of BAP1, implying that this initial growth defect is not a critical factor in BAP1's role as a tumor suppressor.

The cellular response to MT 63 78 included G2/M cell cycle arrest — such cell cycle inhibition was sustained in cells deficient in p53 function, suggesting a p53-independent effect.

The histone modifications are furthermore heritable with cell division, as they are sustained in cell culture over several passages.

This variation was accompanied by a characteristic upregulation of the cell cycle inhibitor p16INK4A, which was noticeable in late passage cells and sustained in senescent cells.

Such a difference might cause the different B-Raf activation dynamics upon EGF stimulation, which are sustained in E1/4 cells and transient in E1 cells.

Interleukin 6 (IL-6 -mediated IL-6 -mediatedcers and actIL-6 -mediatednsignalion 3 (Stransducersphorylandon (activators) is aberrantly sustained in chofangiocarcinoma cells resultranscriptionced myeloid cell leukemia 1 (Mcl-1) expression and resistance to apoptosis.

Upon stimulation with EGF, ligand-induced EGFR degradation was impaired and the expression of phospho-tyrosine 1068 and phospho-p44/42 MAPK was sustained in RBE cells as compared with MMNK-1 cells.