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There used to be a hypothesis that was very popular a while ago, called the decoupling hypothesis, which said that especially in the BRIC economies and emerging markets more broadly growth could be sustained even in the absence of growth in the developed world.
However, this analysis indicated that the virus-induced increases in cytokine levels were sustained even in the absence of significant levels of progeny virus production.
Importantly, our results demonstrate that the acute effects of fructose consumption persist when fructose is consumed over longer periods (10 wks), and in subjects consuming an energy-balanced diet, suggesting that fructose-induced changes of the regulation of key metabolic pathways involved in cellular energy utilization are sustained even in the absence of positive energy balance.
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Together, these studies provide evidence for chromatin-dependent, epigenetic control of gene silencing that is heritable, stable, and self-sustaining, even in the absence of the originating genomic signals.
They show that these currents can sustain oscillations even in the absence of tube growth, a phenomenon that has been observed experimentally [52].
NANOG expression levels are crucial as its forced expression is sufficient to sustain pluripotency even in the absence of extracellular signaling factors such as Leukemia Inhibiting Factor (LIF) [ 6, 7] which are otherwise required for stem cell maintenance.
This activation occurs via cellular protein breakdown leading to recycling of amino acids in lysosomes, which serves to sustain protein synthesis, even in the absence of amino acids coming from the diet, EN, or PN [ 4, 5].
The sustained pro-inflammatory response even in the absence of a productive infection suggests that drugs that control the pro-inflammatory response may be useful in the treatment of patients with severe RSV infection.
This phenomenon reflects the ability of prostatic epithelial cells to sustain growth and proliferation even in the absence of androgen, thus acquiring androgen independency and an aggressive phenotype.
This suggests that Mtb retains a low level of metabolic activity to sustain an energised membrane even in the absence of respiration during hypoxic persistence.
Though initially successful, this form of therapy fails in advanced stages of the disease, as the cells develop the ability to sustain growth and proliferation even in the absence of androgens, thus acquiring androgen resistance [ 1].
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